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How IVF process Works?
IVF process can be understood with the help of certain steps which are explained below.
Ovarian stimulation: The fertility specialist monitors the timing of egg release. Doctor will make sure the hormonal level and other conditions for IVF are normal or not. The doctor watch over produced eggs are appropriate or not.
Egg retrieval: In this step, eggs are taken out from female’s ovary by using needle under light sedation. Further, eggs are placed in a dish containing nutrient media and further it is shifted to the incubator.
Fertilisation: This is the next step called fertilisation where male sperm are taken and mixed with the most active sperm in a special chamber. Then, eggs and sperm are placed in incubator and the process is monitored so that healthy embryo can develop.
Embryo transfer: It is the last step in which the healthiest embryo is transferred. Initially, the doctor examines so that healthy embryo can be selected. With the help of small plastic tubes, the embryo is transferred.
How much time IVF takes?
IVF involves two visits:
(1) One day for checkup / pre-IVF preparation
(2) 15 days for IVF procedure
What is the cost of IVF Program?
As compare to international IVF hospitals the cost of IVF is lower in India. The treatment cost ranges between INR 1,25,000 to 1,50,000. It is purely depends on patient’s medical condition which may vary the cost.
What is IUI Process?
IUI stands for intrauterine insemination, is one of the common techniques of ART (Assisted Reproductive Technology). It allows putting sperm directly to the female’s uterus. In this process, the processed (washed) sperm are used. However, usage of this technique will result in escalating the possibilities of conception.
Is IVF process painful?
No, IVF is not at all painful because the injections used for IVF are purified and injected in subcutaneous form. The egg collection process is done under light sedation which is totally painless. At the time of embryo transfer, anaesthesia is not given but it is a 2 to 5 minutes of process which hardly cause any pain.
What treatment is available for low sperm?
Low sperm count can also be known as oligospermia. One may undergo to ICSI (Intracytoplasmic Sperm Injection) where a single sperm is injected to matured egg. Adapting this treatment will leads to elevate the chances of conceiving. Besides this, the treatment is useful especially in case of male infertility, low sperm motility and poor sperm morphology.
What are the Steps involved in IVF Process
IVF process is a series of procedures. The IVF process steps includes
1. Initial Consultation
In your step by step IVF process, your first step should be meeting up with an IVF specialist. Once all the information has been discussed, the specialist will recommend the best way to proceed.
2. Testing and Ovary Stimulation
The stimulation process will start on the first day of your cycle. Unlike normal, you will be given medications for 8-14 days to encourage the follicles in your ovaries to produce more eggs.
3. Egg retrieval
This procedure takes about 20-30 minutes while you are asleep. Your specialist will use the latest ultrasound technology to guide a needle into each ovary. The average number of eggs collected is 8-15.
4. Sperm Retrieval
Sperm retrieval is done on the same day as that of egg retrieval if you are a couple planning to use fresh sperm in an IVF treatment procedure. In case of frozen or donor eggs, the specialists will keep them ready in the lab.
5. Fertilization
The scientists will now use powerful microscopes to find the eggs from the fluid so they can be taken out of it. Then both eggs and sperm are fertilized in a dish in vitro.
6. Embryo Development
Fertilization of the egg and the sperm results into a zygote which further develops into an embryo. Then the embryo is placed in a special incubator.
7. Embryo Transfer
Here, the scientist prepares the embryo by placing it in a catheter (small tube). Then, he will place the catheter through the cervix into your uterus.
8. Final Pregnancy Test
Two weeks post your embryo transfer; your specialist will conduct a blood test to measure your hCG hormone level. When hCG is detected in your bloodstream, it is a positive sign of pregnancy.
This is the complete step by step IVF process.
How much rest is required after the procedure?
It is one of the most common queries among the couples undergoing IVF treatment. When our patient poses in front of us with these worries, we advise them to think about human body in a scientific way. Even though, embryo is formed artificially in an IVF pregnancy, there is no difference from what happens in the natural cycle. The uterus accepts the embryo in the same way it accepts the naturally fertilised eggs.
It is important to understand that nature has a foolproof plan in everything including the reproductive system where the embryo attaches to the uterine lining very firmly regardless of whether it attaches naturally or artificially. The movements or walk around or even gravity, does not cause the embryo to detach and fall off.
Also, it is a total myth that bed rest after embryo transfer increases success rate of IVF. In fact, research has shown that patients who do complete bed rest after embryo transfer have less success in IVF as compared to patients who continue to do their routine activities. Main reason behind this is that patients who keep themselves engaged in some activities have less stress levels which help in increasing their IVF success. Therefore, the advice of bed rest after IVF procedure is over exaggerated or unrealistic.
What is the success rate of IVF?
Growing from just two fertility clinics in 2015 (Udaipur and Pune) to 94 centres in 2021, Indira IVF has a vast presence across India.  Indira IVF uses various technologies like Electronic witness technology, closed working chambers technology, artificial intelligence (AI), and microfluidics, among others to help its patients.
With the Electronic witness technology, Indira IVF assures its patients of its extent of accountability. This technology ensures sample safety, quality control, and efficiency, where every sample is labelled with an RFID chip.  The closed working chambers technology, on the other hand, is imported from Australia, that provide a long-term stable environment (controlled CO2, temperature, humidity, and volatile organic compound-free atmosphere) for handling gametes, oocytes, embryos, and other tissues dependent on a controlled environment.
Technology and doctors are the most important factors which one should see before choosing the right IVF centre. With the help of such advanced technology and the leading fertility experts of India, Indira IVF has a record IVF success rate of 74 %. Till now, more than 85000 couples have conceived by getting treated at around 94 Indira IVF centes pan India. By leveraging technology and standardising the procedures, we are constantly working towards improving the IVF success rates.
What is the gap period required between 2 unsuccessful cycles?
IVF is planned for the second time only after a thorough diagnosis and analysis of possible causes of failure. On an average, a woman is given 3 months for rehabilitation as IVF cycles gap. During this time, the reproductive system is restored and prepares to receive a new fertilized egg. If after the first IVF, there was a frozen pregnancy, then in this case the rest period lasts about 6 months. In such a situation, there is always chronic endometritis, which needs careful treatment before planning a new pregnancy.
For the second attempt to be successful, sometimes it is enough to make some adjustments to the previous IVF protocol by adding a proper IVF cycles gap. In some cases, a long stimulation cycle is replaced with a short one, or one hormonal preparation is changed for another, while in some others, the dosage is changed.
If no specific complications were identified, and the first IVF attempt was carried out in a natural cycle, that is, hormonal stimulation was not used, then the artificial insemination procedure can be carried out after 2 weeks. This means that in the next menstrual cycle, doctors begin to monitor the dominant follicle and, when favourable conditions are reached, they perform a puncture and egg collection.
When should I opt for IVF?
The IVF procedure can be prescribed in cases where the other fertility treatments have failed, or if the chances of a successful pregnancy are higher with this method than with any other treatment.
If there are no contraindications, the procedure can be carried out simply at the request of the couple by considering that precise time as the right time for IVF.
In which cases, IVF is performed? Tubal-peritoneal factor
Violation of the patency of the fallopian tubes leads to the fact that the egg cannot penetrate into the uterine cavity. In this case, you can either try to restore patency using a surgical laparoscopic operation or perform IVF and implant an already developing embryo into the uterine cavity.
Male factor
This diagnosis is made when the quality of sperm is not high enough. If the number of healthy active sperm is too low to conceive a healthy child, it is better to resort to ART. 
Endometriosis
Mild forms of endometriosis usually respond to surgery and hormonal treatment. If, after the therapy, pregnancy does not occur, then the doctor sends the couple for IVF procedure.
Age-related infertility
Age plays a vital role when we talk about deciding the right time for IVF. With this factor of infertility, it is desirable to supplement the standard IVF procedure with ICSI and assisted hatching methods.
  Anovulation
Anovulation is usually treated with simpler methods, such as hormonal stimulation combined with IUI . But if it’s unsuccessful, you can always use the IVF method.
Unexplained infertility
If it is not possible to establish an accurate diagnosis, and the therapy is unsuccessful, the doctor may advise the couple to resort to the IVF procedure.
What is Cryopreservation?
Cryopreservation procedure allows freezing of the eggs, sperms, or embryos for future use. Generally, in IVF, three types of cryopreservation techniques are followed.
1. Oocyte cryopreservation or Egg Freezing
Oocyte cryopreservation allows you to use frozen eggs at any desired time later in the future. When you feel ready for pregnancy, you can use these preserved eggs to ensure a healthier pregnancy. This reduces your concerns about chromosomal abnormalities, which otherwise increase with age, especially when you are 35 or older. Frozen oocytes can be thawed and then combined with sperms in the clinical lab.
2. Sperm Cryopreservation
It is a process of storing sperms for future use. It helps men to preserve their fertility who are about to have a treatment that can cause infertility such as cancer therapy, prostate or testicular surgery. You can also opt for sperm freezing if you are under the risk of exposure to chemicals or radiation. This procedure is also used in sperm banking.
3. Embryo Cryopreservation
In IVF, embryo cryopreservation is an excellent option for preserving fertility for future use. Many times the extra embryos from an IVF cycle are kept frozen for future use. Embryo cryopreservation provides you another chance to get pregnant if IVF fails for the first time. You will not have to go through the whole IVF procedure again.

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