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Why Endometriosis Happens: Simple Guide to Causes & Risks

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Last updated: December 03, 2025

Overview

Endometriosis is a common gynaecological issue in which uterine-like tissue grows outside the uterus. This article covers why endometriosis happens, the top scientific theories, and the main risk factors to watch for. You’ll also understand how endometriosis causes infertility, whether endometriosis can cause cancer, and the complications that follow if the condition is unaddressed. Perfect for women seeking clear, evidence-based knowledge.

Introduction

It is also helpful in clarifying concerns, such as the potential link between endometriosis and cancer. Identifying the underlying causes allows doctors to prevent symptoms from escalating by planning highly targeted treatments.

Endometriosis is a condition where endometrial-like tissue grows outside the uterus, affecting pelvic organs and causing inflammation. Understanding endometriosis causes is necessary for explaining why endometriosis happens and recognising early symptoms. Because endometriosis causes infertility in some women, awareness of the condition’s triggers supports timely treatment.

What are the Causes of Endometriosis?

Many women want to understand, “What are the causes of endometriosis?” Although the exact cause isn’t confirmed, doctors believe several factors work together. Retrograde menstruation, where menstrual blood flows backwards, is one explanation.

Beyond the main causes, hormonal balance, immunity, and genetics matter. Some cells transform into endometrial tissue, and embryonic cells may become abnormally active years later.

Common Causes of Endometriosis

Understanding the possible endometriosis causes can make the diagnosis feel less overwhelming.

  • Retrograde menstruation: Menstrual blood may flow backwards and deposit cells in the pelvis.
  • Peritoneal cell change: Abdominal lining cells can transform under certain conditions.
  • Embryonic cell changes: Some leftover cells from early development may activate at puberty.
  • Surgical scars: C-sections or hysterectomies can allow endometrial tissue to implant on scars.
  • Cell movement: The cells may spread through the bloodstream or lymph system.
  • Immune issues: When immunity is weak, abnormal tissue can grow unchecked.

Risk Factors Associated with Endometriosis

Certain factors increase the risk of developing endometriosis, including:

  • Family History: Women with a close relative (mother, sister, or daughter) who has endometriosis have a significantly higher risk, indicating a strong genetic connection.
  • Early Menstruation: Starting periods before age 11 increases exposure to menstrual cycles over a lifetime, raising the likelihood of endometrial tissue growth outside the uterus.
  • Long or Heavy Menstrual Cycles: Women who experience prolonged bleeding or naturally heavy periods face a greater risk because of increased menstrual flow.
  • Short Cycle Intervals: Having cycles shorter than 27 days increases the frequency of menstruation, which may contribute to retrograde flow.
  • Low Body Weight: Very low body fat or being underweight can disrupt normal estrogen levels. Since endometriosis is estrogen-dependent, hormonal imbalance may increase risk.
  • Uterine Abnormalities: Structural issues such as a tilted uterus, cervical stenosis, or congenital abnormalities can hinder the normal outflow of menstrual blood and lead to retrograde menstruation.

Understanding these endometriosis risk factors enables timely monitoring and early medical intervention.

Complications of Endometriosis

Living with endometriosis can involve multiple complications. Infertility is a key issue, as endometriosis causes infertility by damaging reproductive organs, creating adhesions, and affecting egg quality. Chronic pelvic pain may gradually worsen, affecting daily activities.

Adhesions and scar tissue can make organs stick together, leading to digestive or urinary discomfort. Many women worry, “can endometriosis cause cancer?” Although uncommon, severe or long-term endometriosis slightly raises ovarian cancer risk. Recognising symptoms early, seeking treatment, and regular monitoring can reduce endometriosis complications, manage pain, and preserve fertility.

When to Seek Medical Help

Your reproductive wellness matters deeply, and there are key signals you should pay attention to:

  • Significant Pelvic Pain: Noticeable pain in the pelvic or abdominal region, especially tied to your menstrual cycle, could indicate a deeper concern. Pain severe enough to interrupt work, exercise, or routine life warrants gentle, prompt care.
  • Challenges with Conception: Finding it difficult to conceive can be an isolating journey. This may suggest issues like endometriosis or a hormonal imbalance. Scheduling an early evaluation with a specialist can bring both answers and hope.
  • Ongoing or Strange Symptoms: Don't dismiss heavy menstrual bleeding, painful bowel movements, persistent bloating, or chronic fatigue as "just normal." These are often signs of reproductive or hormonal issues that deserve a professional look.
  • Menstrual Changes: If you notice shifts in your cycle, like sudden irregularity, missed periods, or bleeding that lasts too long over several months, it's a sign you should seek early medical evaluation.

Conclusion

Ignoring symptoms is not an option. Understanding the root causes of endometriosis is essential for immediate symptom recognition and securing timely treatment. Though the exact cause is unknown, familiarising yourself with contributing factors allows you to proactively reduce severe pain and safeguard your fertility. Act fast: early diagnosis prevents life-altering complications like chronic pain and adhesions. If your symptoms are disrupting daily life, consult a gynaecologist now.

Common Questions Asked

What are the main causes of endometriosis?

 

Major contributing factors are menstruation flowing backward, cell changes, transformation of embryonic cells, immune system failure, surgical scar implants, and cell movement via blood/lymph.

Can endometriosis cause infertility?

 

Yes. Endometriosis causes infertility by damaging reproductive organs, creating scar tissue, and affecting ovulation.

Can endometriosis cause cancer?

 

Endometriosis slightly increases the risk of ovarian cancer, but this complication is rare.

Is endometriosis hereditary?

 

Yes. A family history increases the likelihood of developing endometriosis.

Can lifestyle changes prevent endometriosis?

 

Lifestyle changes cannot fully prevent it, but may reduce symptom severity by balancing hormones and lowering inflammation.

Does family history increase my risk of endometriosis?

 

Yes. Women with immediate family members who have endometriosis are at higher risk.

What are the common complications of endometriosis?

 

Complications include infertility, chronic pain, adhesions, and a small increased risk of ovarian cancer.

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