Male Infertility: Causes, Symptoms and Treatment Explained

Last updated: January 23, 2026

Overview

While male infertility affects millions worldwide, it remains a topic many find difficult to discuss. This comprehensive guide explores what causes infertility in men, including lifestyle factors and hormonal imbalances. It also covers the key signs to watch for, diagnostic procedures and the treatments available. By understanding these factors, you can address fertility challenges and make informed decisions about your reproductive health.

For many men, struggling to conceive can feel frustrating and isolating; especially when people often assume fertility issues are only on the woman’s side. Male infertility is more common than most realise, contributing solely to about 20% of infertility cases and playing a role in another 30-40%.

This matters because fertility challenges can affect more than just starting a family; they can impact your confidence, your relationship and even your focus on work or business. The good news is that many causes of male infertility are treatable. Some need medical care, while others improve with lifestyle changes like diet, stress management and healthy habits.

If you’ve been trying to conceive for over a year without success, it’s important to explore both partners’ fertility. This guide will help you understand what causes infertility in men, including its causes, warning signs, diagnostic tests and treatment options; so you can take informed steps toward building your family.

What Causes Infertility in Men?

Male infertility occurs when there are problems with sperm production, function or delivery. These issues are often caused by genetic factors, medical conditions or lifestyle choices.

For natural conception, a man must produce healthy sperm that can travel through the reproductive system and reach the female reproductive tract. Any disruption at these stages can lead to infertility.

What Are the Most Common Medical Causes of Male Infertility?

The main medical causes of male infertility include varicocele, infections, hormonal disorders and genetic conditions that affect sperm production or function.

Varicocele

Varicoceles are swollen veins in the scrotum and the most common treatable cause of male infertility, affecting 20-40% of infertile men. They increase testicular temperature, which can reduce sperm quality and production. Many men are unaware they have varicocele until fertility testing.

Infections and Inflammation

Certain infections can harm sperm or block sperm passage:

  • Epididymitis (inflammation of the sperm storage tube)
  • Orchitis (testicular inflammation)
  • Sexually transmitted infections (gonorrhoea, chlamydia)
  • Prostatitis (prostate inflammation)
    Even after treatment, scarring may block sperm pathways.

Hormonal Disorders

Sperm production relies on hormones from the pituitary, hypothalamus and testicles. Imbalances in testosterone, FSH, LH or thyroid hormones can significantly affect fertility.

Genetic Conditions

Some genetic abnormalities can impair fertility:

  • Klinefelter syndrome (extra X chromosome)
  • Y chromosome microdeletions
  • Cystic fibrosis mutations affecting the vas deferens
  • Kallmann syndrome (affecting hormone production)

How Do Lifestyle Factors Affect Male Fertility?

Lifestyle choices can significantly impact male fertility by affecting sperm quality, count and motility. Smoking, excessive alcohol, drug use, obesity, heat exposure and chronic stress are common factors that reduce fertility.

  • Smoking and Substance Use

    Tobacco smoke contains harmful chemicals that can damage sperm DNA and lower sperm count. Studies show smokers have about 23% lower sperm concentrations than non-smokers. Marijuana, cocaine and anabolic steroids can also severely impair sperm production.
  • Alcohol Consumption:

    Heavy drinking can reduce testosterone levels and sperm quality. Chronic alcohol use may cause liver damage, further disrupting hormone balance. Moderate drinking usually does not cause fertility problems.
  • Weight and Diet:

    Obesity or being significantly underweight can disrupt hormone levels and sperm production. Excess body fat converts testosterone to oestrogen, creating hormonal imbalances. A diet lacking antioxidants, vitamins or minerals can also impair sperm health.
  • Heat Exposure:

    Sperm production requires temperatures slightly below body temperature. Frequent hot baths, saunas, laptops on the lap or tight underwear can temporarily reduce sperm production.
  • Stress:

    Chronic stress affects hormone levels, reducing sperm concentration and sexual function.

What Are the Symptoms of Male Infertility?

Many men with infertility do not experience obvious symptoms, making the condition difficult to detect. Often, the only sign is the inability to achieve pregnancy after a year of regular, unprotected intercourse.

Some men may notice signs that indicate underlying fertility issues:

Physical Signs

  • Small or firm testicles
  • Swelling in the scrotal area
  • Reduced facial or body hair
  • Breast tissue development (gynaecomastia)

Sexual Function Changes

  • Difficulty maintaining an erection
  • Problems with ejaculation
  • Reduced sexual desire
  • Small ejaculate volume

Hormonal Indicators

  • Fatigue
  • Difficulty concentrating
  • Mood changes
  • Weight gain

How Is Male Infertility Diagnosed?

Male infertility is diagnosed through a combination of semen analysis, physical examination and additional tests based on initial findings.

Semen Analysis

This is the primary test for male fertility. A semen sample is analysed for:

  • Sperm concentration (count per millilitre)
  • Total sperm count
  • Motility (percentage of moving sperm)
  • Morphology (percentage of normally shaped sperm)
  • Semen volume and pH
  • White blood cell count (to detect infection)

Physical Examination

The doctor examines the genitals for abnormalities, varicoceles or signs of hormonal issues. They also review medical history, sexual history, medications and lifestyle factors.

Additional Testing

If needed, further tests may include:

  • Hormone blood tests (testosterone, FSH, LH, prolactin)
  • Genetic testing for chromosomal abnormalities
  • Testicular biopsy to check sperm production
  • Specialised sperm function tests
  • Imaging studies (scrotal or transrectal ultrasound)
  • Post-ejaculation urinalysis (to check for retrograde ejaculation)

What Are The Treatments for Male Infertility?

Treatment for male infertility depends on the underlying cause and includes medications, lifestyle changes, surgical procedures and assisted reproductive technologies (ART).

Medical Treatments

  • Hormone replacement or stimulation therapy for hormonal imbalances
  • Antibiotics for infections
  • Medications to improve ejaculatory function
  • Surgery to correct blockages in the reproductive tract
  • Varicocele repair to improve sperm quality
  • Sperm retrieval procedures for men with no sperm in the ejaculate

Lifestyle Modifications

Simple lifestyle changes can improve sperm health within 2-3 months:

  • Quit smoking and limit alcohol intake
  • Maintain a healthy weight
  • Follow a balanced diet rich in antioxidants
  • Exercise regularly and avoid excessive heat
  • Use stress-reduction techniques
  • Avoid hot baths and tight clothing

Assisted Reproductive Technologies (ART)

  • Intrauterine Insemination (IUI): Sperm is collected, processed and placed into the uterus; best for mild to moderate sperm issues.
  • In Vitro Fertilisation (IVF): Eggs are fertilised with sperm in a lab and embryos are transferred to the uterus.
  • Intracytoplasmic Sperm Injection (ICSI): A single sperm is injected into an egg; used for low sperm count or poor quality.
  • Sperm donation: An option when male infertility cannot be overcome naturally

Can Male Infertility Be Prevented?

Not all causes of male infertility can be prevented, but the risk can be reduced through healthy lifestyle choices and protective measures.

  • Maintain a healthy weight and follow a balanced diet
  • Exercise regularly and manage stress effectively
  • Avoid smoking, limit alcohol and stay away from recreational drugs
  • Protect against sexually transmitted infections using safe practices
  • Seek prompt medical attention for testicular pain, swelling or other reproductive issues

Conclusion

Male infertility is common, but it is not a dead end. Understanding the causes, from medical conditions to lifestyle factors, empowers you to take control of your reproductive health. Early evaluation can identify issues quickly, allowing timely treatment and lifestyle changes that often improve fertility.

For men, taking small but consistent steps, like improving diet, managing stress, avoiding harmful substances and addressing medical concerns, can make a real difference. Modern treatments, including assisted reproductive technologies, offer solutions even in challenging cases. The key takeaway is to not ignore fertility concerns, start the conversation with your doctor and take proactive steps today to protect your future family.

Common Questions Asked

How long should couples wait before seeking help for male infertility?

 

Couples under 35 should consider a fertility evaluation after one year of trying without success. For couples where the female partner is over 35, evaluation is recommended after six months. Early assessment can detect treatable issues before they worsen.

Does male fertility decline with age?

 

Yes, sperm quality and hormone levels gradually decline with age. While men can remain fertile into their 70s, advancing age can increase the risk of genetic issues and lower chances of conception.

Can stress and mental health affect fertility?

 

Chronic stress can reduce testosterone levels, sperm count and motility. Mental health issues like anxiety or depression can also lower sexual desire and disrupt regular sexual activity, indirectly impacting fertility.

How long does it take for lifestyle changes to impact fertility?

 

Lifestyle improvements such as quitting smoking, reducing alcohol, eating a balanced diet and managing stress may take 2-3 months to show measurable improvement in sperm quality, which aligns with the sperm production cycle.

Should both partners be evaluated together?

 

Yes. Evaluating both partners simultaneously provides a complete picture of fertility factors and can speed up diagnosis and treatment. It also helps avoid unnecessary delays if issues exist on both sides.

**Disclaimer: The information provided here serves as a general guide and does not constitute medical advice. We strongly advise consulting a certified fertility expert for professional assessment and personalized treatment recommendations.
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