“Qualis” or “Microfluidic Sperm Sorter” is a cutting-edge technology where highly motile and structurally normal spermatozoa with good DNA integrity are separated from semen so that they can be used to fertilize human oocytes. This technology is a boon to the couples facing difficulty in achieving parenthood due to male factor.
Qualis technique is based on a principle called microfluidic. It is observed that physiologically and genetically perfect sperms exhibit a high grade of forward motility. In Qualis technique an embryologist takes advantage of this property of sperms. In a simplified way, the sperms are made to race in a narrow stream of fluid. The heathiest sperms win this race and get collected in a specific chamber. Those sperms are separated and used to fertilize ovum by ICSI process.
This is basically an add on method designed for couples suffering from male factor infertility. Qualis technique is extremely helpful in the cases where the male partner has deficient amount of structurally normal sperms (teratozoospermia) or where sperms show a higher DNA fragmentation index (DFI). Patients where good quality embryos were not formed or IVF failed in previous cycle despite of a normal semen analysis report may also opt for this technique.
It has been observed that the quality of human sperms is deteriorating in all parameters with each decade. This may be due to environmental factors or due to changing lifestyle. Conventional semen preparation techniques are associated with causing DNA damage to the sperm nucleus leading to failure in IVF cycle. The main advantage of Qualis technique is its ability to yield morphologically normal sperms with intact DNA devoid of dead sperms or any debris that can be used in an IVF cycle.
Research has proved that use of Qualis technique leads to higher fertilization rate, formation of better embryos as well as increase in pregnancy rates after ICSI procedure.
Success rate in IVF or ICSI is greatly dependent on the ability of the laboratory to produce high grade embryos. This can be obtained by selection of the right sperm with perfect structure and highest DNA integrity. Qualis technique assists in attaining this goal. Hence it is a prudent idea to opt for this game changing revolutionary technology in the field of IVF in order to enhance the chance of achieving success in IVF treatment.
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