Skip to main content


Endometrial hyperplasia (thick endometrium) occurs when the lining of the uterus grows too thick. Learn about endometrium hyperplasia causes & treatment at Indira IVF.

The human body is a complex network of interconnected systems, each playing a vital role in maintaining overall health and functioning. Among these systems, the female reproductive system holds significant importance as it plays a pivotal role in the continuation of human life. However, there are various conditions that can affect the normal functioning of this system, one of which is Endometrial Hyperplasia. In this article, we will delve into the details of Endometrial Hyperplasia, exploring its causes, symptoms, diagnosis, treatment options, and how Indira IVF can provide assistance in managing this condition.

What is Endometrial Hyperplasia?

Endometrial hyperplasia is a condition characterized by the abnormal growth of cells in the uterine lining, leading to a thick endometrium. This condition occurs when there is an excess growth of cells in the endometrial lining, resulting in the thickening of the tissue. Normally, the endometrium undergoes cyclic changes in response to hormonal fluctuations, preparing the uterus for potential pregnancy. However, in cases of Endometrial Hyperplasia, this process becomes disrupted, leading to potential complications, such as thickened endometrium which can increase the risk of further health issues, including endometrial cancer.

Types of Endometrial Hyperplasia

Endometrial Hyperplasia is classified into different types based on the appearance of the endometrial cells under a microscope. The main types include:

1. Simple Hyperplasia: In this type, there is an increase in the number of glandular cells in the endometrium, which can result from hormonal imbalances.

2. Complex Hyperplasia: This type involves both an increase in glandular cells and changes in the architecture of the glands themselves. Complex hyperplasia is considered to have a higher risk of progressing to endometrial cancer compared to simple hyperplasia.

3. Atypical Hyperplasia: Atypical hyperplasia is characterized by abnormal changes in the appearance of the endometrial cells. This type has a higher risk of developing into endometrial cancer and requires careful monitoring and intervention.

3. Atypical Hyperplasia: Atypical hyperplasia is characterized by abnormal changes in the appearance of the endometrial cells. This type has a higher risk of developing into endometrial cancer and requires careful monitoring and intervention.

Causes of Endometrial Hyperplasia (Thick Endometrium Causes)

The underlying Causes of Endometrial Thickening are often linked to hormonal imbalances, specifically an imbalance between estrogen and progesterone. Estrogen promotes the growth of the endometrial lining, while progesterone helps to control its growth and prepare it for pregnancy. Some of the common Endometrial Hyperplasia Causes are:

1. Obesity: Excess fat tissue can produce more estrogen, disrupting the hormonal balance.

2. Polycystic Ovary Syndrome (PCOS): PCOS is associated with elevated levels of estrogen and insufficient progesterone.

3. Hormone Replacement Therapy (HRT): Prolonged use of estrogen without adequate progesterone can lead to hyperplasia.

4. Anovulation: Irregular ovulation or failure to ovulate can disrupt the normal hormonal cycle.

5. Diabetes: Uncontrolled diabetes can affect hormonal regulation.

6. Certain medications: Some medications can impact hormonal balance and increase the risk of Endometrial Hyperplasia.

Symptoms of Endometrial Hyperplasia (Thick Endometrium Symptoms)

Some of the common Endometrial Hyperplasia Symptoms (Endometrial Thickening Symptoms) include:

1. Abnormal uterine bleeding: Heavy, prolonged, or irregular menstrual periods.

2. Pelvic pain or discomfort: Pain in the pelvic area may be experienced.

3. Unusual discharge: Abnormal vaginal discharge may occur.

4.Infertility: Difficulties in getting pregnant can arise due to hormonal disruptions.

Endometrial Hyperplasia Risk & Complications

One of the primary concerns associated with Endometrial Hyperplasia is the potential progression to endometrial cancer. Atypical hyperplasia, in particular, carries a higher risk of developing into cancer. Therefore, prompt diagnosis and management are essential to prevent this progression. Additionally, the condition can impact fertility, making it difficult for individuals to conceive.

Endometrial Hyperplasia Diagnosis

Diagnosing Endometrial Hyperplasia typically involves a combination of medical history assessment, physical examination, and diagnostic tests. These tests may include:

1.Transvaginal Ultrasound: This imaging technique provides a clear view of the endometrium's thickness and structure.

2. Endometrial Biopsy: A small tissue sample is taken from the endometrium and examined under a microscope to determine the type of hyperplasia.

3.Hysteroscopy: A thin, flexible tube with a camera is inserted into the uterus to visualize the endometrial lining.

Getting Pregnant with Endometrial Hyperplasia

Endometrial Hyperplasia can pose challenges to conception due to its impact on the uterine environment. However, with proper medical intervention and management, many individuals with this condition can achieve successful pregnancies. Fertility treatments, such as in vitro fertilization (IVF), may be recommended to increase the chances of conception.

Treatment for Endometrial Hyperplasia (Thick Endometrium Treatment)

The choice of treatment for Endometrial Thickness depends on factors such as the type of hyperplasia, severity, and the individual's reproductive goals. Some of the Endometrial Hyperplasia Treatment options include:

1. Hormonal Therapy: Progestin therapy, which involves taking synthetic progesterone, is often used to regulate and control the growth of the endometrium.

2. Dilation and Curettage (D&C): In cases of abnormal bleeding, a D&C procedure may be performed to remove excess tissue from the uterine lining.

3. Hysterectomy: In severe cases or when other treatments are not effective, a hysterectomy (removal of the uterus) may be recommended, especially for individuals who have completed their family planning.

Frequently Asked Questions (FAQs)

1. Can Endometrial Hyperplasia be prevented?

While it may not always be preventable, maintaining a healthy lifestyle, managing weight, and addressing hormonal imbalances can reduce the risk.

2. Is Endometrial Hyperplasia the same as Endometriosis?

No, endometriosis involves the presence of endometrial tissue outside the uterus, while Endometrial Hyperplasia refers to the thickening of the uterine lining.

3. Does Endometrial Hyperplasia always lead to cancer?

No, not all cases of Endometrial Hyperplasia progress to cancer. Regular monitoring and appropriate treatment can prevent this progression.

How Indira IVF Can Help?

Endometrial Hyperplasia is a condition that highlights the intricate balance of hormones within the female reproductive system. While it can pose challenges to fertility and health, timely diagnosis and proper management can greatly influence the outcome. Advances in medical technology and fertility treatments provide hope and solutions for individuals dealing with Endometrial Hyperplasia. By raising awareness about this condition and seeking expert guidance, individuals can navigate their journey toward better reproductive health.

Indira IVF is a leading institution that specializes in fertility treatments and reproductive healthcare. With a team of experienced medical professionals and cutting-edge technology, Indira IVF offers a range of treatments, including in vitro fertilization (IVF), to help individuals overcome fertility challenges, including those related to Endometrial Hyperplasia. The expertise of our team, coupled with personalized treatment plans, ensures that patients receive the best possible care on their path to building a family. If you're seeking guidance and support for managing Endometrial Hyperplasia while pursuing your dream of parenthood, visit your nearest Indira IVF centre today or call 18003092323 to book an appointment with our Fertility Experts.


Tools to help you plan better

Get quick understanding of your fertility cycle and accordingly make a schedule to track it

© 2023 Indira IVF Hospital Private Limited. All Rights Reserved.