What is the difference between IVF and ICSI?
The way the sperm fertilises the egg is the main difference between IVF and ICSI. The egg and sperm (of which there are many) are left in a petri dish to fertilise on their own during IVF. In ICSI, one sperm is directly injected into the egg.
How ICSI can help in infertility?
ICSI is a IVF that is used primarily for the treatment of severe cases of male-factor infertility. ICSI involves the injection of a single sperm directly into a mature egg.
What causes ICSI failure?
The inability of the sperm to activate the oocyte is the most common reason for unsuccessful fertilisation following ICSI utilising round-head sperm. Fertilization failure can also be caused by nuclear decondensation arrest and/or premature chromosomal condensation in some types of globozoospermia.
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