Intrauterine insemination (IUI) is a procedure in Assisted Reproductive Technology (ART) that is primarily used in cases of male infertility, unexplained infertility, and cervical hostility. Intrauterine means “inside the uterus” thus, intrauterine insemination is the process wherein the best quality sperms are introduced into the uterus to fertilise the egg. The objective here is to bring the sperms as close to the egg as possible.
Understanding the IUI procedure step-by-step is essential to aligning expectations to that of the success of the technique.
The first step is to consult with a fertility/IVF specialist in order to discuss medical history. IVF does not guarantee 100% success and hence, it is imperative that risks and side effects of the procedure are understood.
This is followed by blood tests and scans where various parameters such as hormone levels are checked in females as well as ultrasound is performed to ascertain ovarian reserve. These are also performed to check for any pre-existing conditions such as diabetes or hypertension in the partners.
After the results are out, a follow-up consultation is done with the specialist at Indira IVF. The treatment plan is discussed, consent is taken from the patient, more screening tests are done.
A hysterosalpingogram is performed in the female to ensure that at least one functional fallopian tube exists that can aid ovulation.
Semen analysis is performed on the male partner’s semen sample to check sperm count, morphology and mobility.
After baseline scan, hormonal injection may be administered to stimulate ovaries to develop egg for ovulation.
Regular monitoring is performed through scans and blood tests to observe response to drugs.
A semen sample is taken from the male partner or a donor, as the case may be.
Sperm wash and microfluidics are performed to select the best quality sperms and remove debris and seminal fluid.
Inseminate is prepared with a determined concentration of the semen sample.
The time of ovulation is closely monitored in the female partner with the help of ultrasound and blood tests. In some cases, the patient may even take fertility medication in order to stimulate the process.
On the day of ovulation, an instrument called speculum is used to open the walls of the vagina and open up the cervix. A thin, flexible catheter is then placed inside the cervix to inject the inseminate into the uterus, taking the sperms as close to the eggs as possible. This procedure takes about 5-10 minutes, and the patient may experience a little cramping which goes away after some time.
A beta-human chorionic gonadotropin (βhCG) test is taken two weeks after the IUI process to determine if the process led to a pregnancy.
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